Shumiya cataract rat
WebThe Shumiya cataract rat (SCR) and normal control rat strains of NC1 and NC2 were established. Mean cataract appearance in adult SCR rats was 66.7%, and embryo death … WebApr 7, 2024 · By positional cloning and genotyping in Shumiya cataract rats, Mori et al. (2006) identified hypomorphic mutations in the Lss gene and the Fdft1 gene (), as well as a null mutation in Lss.Cataract onset was associated with the specific combination of Lss and Fdft1 mutant alleles that decreased cholesterol levels in cataractous lenses to about 57% …
Shumiya cataract rat
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http://www.anim.med.kyoto-u.ac.jp/model/shumiya/SCR.html WebInomata M, Hayashi M, Shumiya S, Kawashima S, Ito Y. Aminoguanidine-treatment results in the inhibition of lens opacification and calpain-mediated proteolysis in Shumiya Cataract Rats (SCR). J Biochem. 2000;128(5):771–776. 41.
WebAug 4, 2024 · Six-week-old Shumiya cataract rats were used to perform experiments. The right eye of each rat was injected with TAT-HA-Prdx6 WT-NPs or TAT-HA-Prdx6 K122/142R-NPs, whereas the left eyes were administered with TAT-HA-Prdx6 Inactive-mutant-NPs. The subconjuctival injection was made using micro-syringes fitted with 30-gauge needles. WebOct 1, 2001 · Aminoguanidine-treatment results in the inhibition of lens opacification and calpain-mediated proteolysis in Shumiya cataract rats (SCR). Inomata M, Hayashi M, Shumiya S, Kawashima S, Ito Y. J Biochem, 128(5):771-776, 01 Nov 2000 Cited by: 23 articles PMID: 11056389
WebThe Shumiya cataract rat (SCR) is a hereditary cataractous strain. It is thought that the continuous occurrence of poorly differentiated epithelial cells at the bow area of the lens … WebThe Shumiya cataract rat (SCR) is a hereditary cataract model in which lens opacity appears spontaneously in the nuclear and perinuclear portions at 11-12 weeks of age.
WebSix-week-old Shumiya cataract rats were used to perform experiments. The right eye of each rat was injected with TAT-HA-Prdx6 WT-NPs or TAT-HA-Prdx6 K122/142R-NPs, whereas the left eyes were administered with TAT-HA-Prdx6 Inactive-mutant-NPs. The subconjuctival injection was made using micro-syringes fitted with 30-gauge needles.
WebOct 1, 2001 · Aminoguanidine-treatment results in the inhibition of lens opacification and calpain-mediated proteolysis in Shumiya cataract rats (SCR). Inomata M, Hayashi M, … how many different human genders are thereWebcataract drug for human cataracts has not yet been intro-duced. In studies to develop anti-cataract drugs, the selection of the experimental animal is very important. The UPL rat (UPLR), Shumiya cataract rat (SCR) and Ihara cataract rat (ICR/f; ICR) are hereditary cataractous strains, and it has been shown that these rats provide useful models ... high temps in usa todayhigh temps in indiaWebLens reconstruction after mature cataract in SCR rat. @article{Okano1999LensRA, title={Lens reconstruction after mature cataract in SCR rat.}, author={Takuya Okano and Shigekazu Uga and S. Ishikawa and Akiko Hara and Seigou Shumiya}, journal={Japanese journal of ophthalmology}, year={1999}, volume={43 5}, pages={ 363-7 } } high temporal validityWebNov 2, 2024 · The Shumiya cataract rat (SCR) is a model for hereditary cataract. Two-thirds of these rats develop lens opacity within 10-11 weeks. Onset of cataract is attributed to … high ten services clinton laWebThe role of proteolytic enzymes in Shumiya cataract rats in alterations to lens proteins during cataract formation was studied immunohistochemically using antibodies against exopeptidases, such as lysosomal dipeptidyl peptidase II (DPP II), cytosolic dipeptidyl peptidase III, and soluble and membrane-bound alanyl aminopeptidases, and against … high tempurture ruin pillsWebJul 21, 2024 · We previously designed ophthalmic nanosuspensions of LAN (LAN-ONSs) and reported that repeated instillation of LAN-ONSs attenuated the slight collapse of the lens structure in Shumiya cataract rats (SCR), although the serious structural collapses were not reversed with the instillation of LAN-ONSs, and repeated instillation could not reverse or ... high tenacity nylon