Nettet28. feb. 2024 · There are several potential sources of TGF-β1 in the liver that may contribute to fibrosis, including HSCs themselves, macrophages, hepatocytes, cholangiocytes, and fibroblasts, 16 but the cellular source(s) of TGF-β1 remain unclear. We previously demonstrated that platelet-derived TGF-β1 contributes to cardiac fibrosis … NettetRecombinant Human TGF-β1 derived from HEK293 cells is a 25.0 kDa protein with each subunit containing 112 amino acid residues, linked by a single disulfide bond. Source: …
Ultra-LEAF™ Purified anti-mouse/human LAP (TGF-β1) …
Nettet3. aug. 2024 · AAV-mediated delivery of TGF-β1 rescued degenerating cones in 3 mouse models of RP carrying different pathogenic mutations. Treatment with TGF-β1 protected vision, as measured by 2 behavioral assays, and could be pharmacologically disrupted by either depleting microglia or blocking the TGF-β receptors. Nettet7. apr. 2024 · Background Radiotherapy is widely applied in breast cancer treatment, while radiotherapy resistance is inevitable. TGF-β1 has been considered to be an endogenous factor for the development of radiotherapy resistance. As a large portion of TGF-β1 is secreted in an extracellular vesicles-associated form (TGF-β1EV), particularly in … unscramble the letters to form words
TGF-beta 1 Products: R&D Systems
NettetMouse TGF-β1, amino acids (Ala279-Ser390) (Accession # NP_035707) was expressed in CHO cells. Molecular Mass. The 112 amino acid recombinant protein has a predicted molecular mass of approximately 12.8kD. The DTT-reduced and non-reduced protein migrate at approximately 12.5 kD and 25 kD respectively by SDS-PAGE. NettetCatalog Number: 500-M66. Description: Preparation: Produced in BALB/c mice immunized with highly pure Recombinant Human TGF-β1. Anti-Human TGF-β1-specific antibody … NettetLMCD1 and mesenchymal markers were upregulated in obstructed kidney tissues of mice at 21 days after unilateral ureteral obstruction surgery compared with the tissues in sham mice. Next, we demonstrated that TGF-β1 significantly increased LMCD1 expression through Smad-mediated transcription in HK-2 cells in vitro. unscramble the word spanish