Buthionine sulfoximine翻译
WebApr 10, 2024 · An inhibitor of cystine uptake was identified to suppress glutathione biosynthesis, leading to ferroptosis, a novel iron‑dependent form of cell death that differs from apoptosis and necrosis. Glutamate‑cysteine ligase (GCL) is the rate‑limiting enzyme in the glutathione biosynthesis pathway. Buthionine sulfoximine (BSO), a GCL inhibitor ... http://www.dictall.com/indu/090/0898657A25C.htm
Buthionine sulfoximine翻译
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WebButhionine sulphoximine 释义: a chemical compound used in the treatment of cancer 意思、发音、翻译及示例 ... Administration of buthionine sulfoximine during hypoxic … Buthionine sulfoximine (BSO) is a sulfoximine derivative which reduces levels of glutathione and is being investigated as an adjunct with chemotherapy in the treatment of cancer. The compound inhibits gamma-glutamylcysteine synthetase, the enzyme required in the first step of glutathione synthesis.
WebThe effects of buthionine sulfoximine on the proliferation and apoptosis of biliary tract cancer cells induced by cisplatin and gemcitabine. Oncol Lett. 2016 11(1):474-480. Chen T, Zhang YH, Wang HL, Chen W, Wang J (通讯作者) WebCAS: 83730-53-4: Molecular Formula: C 8 H 18 N 2 O 3 S: Molecular Weight (g/mol) 222.31: MDL Number: MFCD00067000: InChI Key: KJQFBVYMGADDTQ-CVSPRKDYSA-N: Synonym: l-buthionine-sulfoximine, l-buthionine sulfoximine, 2s-2-amino-4-butylsulfonimidoyl butanoic acid, l-buthionine-s,r-sulfoximine, l-buthionine s,r …
WebL-Buthionine-sulfoximine (L-BSO); >= 97% TLC; This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC 1280), a biologically … Web2) methionine sulfoximine. 蛋氨酸亚砜酰亚胺. 3) Metsox. 蛋氨酸亚砜. 1. Sulfur of gelatin macromolecule contains three chemical states: S OO group of Metson,S O group of Metsox and -S- of Met. 硫在明胶中主要以三种化学形态存在:蛋氨酸砜中的SOO基团,蛋氨酸亚砜中的SO基团,蛋氨酸中的-S-基团。.
Web"sulfoximine,buthionine" 中文翻译: 《英文msh词典》Sulfoximine,Buthionine ; [入口词] Sulfoximine,Buthionine ; [主题词] Buthionine Sulfoximine ; [药动学] Radiation-Sensitizing Agents ; [英文释义] A synthetic amino acid that depletes glutathione by irreversibly inhibiting gamma-glutamylcysteine synthetase. Inhibition of this ...
WebApr 6, 2024 · Cayman Chemical社のButhionine Sulfoximineです。Cayman Chemical社ではプロスタグランジンやステロイドホルモンをはじめとする高品質な低分子化合物などを販売しています。生理活性や阻害効果を有する物質も多数取り揃えております。※本製品は研究目的用にのみ販売しております。 treyarnon beach webcamWebBSO (L-Buthionine-(S,R)-sulfoximine, L-Buthionine sulfoximine, l-BSO) is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase … treyarnon bay surf hireWebL-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively. - Mechanism of Action & Protocol. tennant company reviewsWebIntroduction: Estrogen deprivation using aromatase inhibitors is one of the standard treatments for postmenopausal women with estrogen receptor (ER)-positive breast cancer. However, one of the consequences of prolonged estrogen suppression is acquired drug resistance. Our group is interested in studying antihormone resistance and has … tennant company tickerWebGolgi SNAP receptor complex 1 (GS28) has been implicated in vesicular transport between intra-Golgi networks and between endoplasmic reticulum (ER) and Golgi. treyarnon bay tidestreyarnon beach shop facebookWebProduct Description. L-Buthionine- (S,R)-sulfoximine is an irreversible inhibitor of γ-glutamylcysteine synthetase (K i = 25 µM). 1 It inhibits the proliferation of ZAZ and M14 melanoma cells, as well as A2780 ovarian and MCF-7 breast cancer cells (IC 50 s = 4.9, 18, 8.5, and 26.5 µM, respectively). 2 L-Buthionine- (S,R)-sulfoximine (100µM ... treyarnon beach shop facebook posts